5-Amino-1MQ 10 mg

5-Amino-1MQ – 10 mg Lyophilized Vial

Chemical Information:

• Molecular Formula: C₇H₁₁N₅

• Molecular Weight: 165.20 g/mol

• Chemical Name: 5-Amino-1-methylquinolin-1-ium

• Formulation Type: Lyophilized powder for reconstitution

Description:
5-Amino-1MQ is a small-molecule experimental compound that functions as a methyltransferase inhibitor, particularly targeting nicotinamide N-methyltransferase (NNMT). This enzyme plays a role in regulating cellular energy metabolism, making 5-Amino-1MQ a focus of research into obesity, metabolic disorders, and age-related energy decline. By modulating NNMT activity, 5-Amino-1MQ may influence NAD⁺ levels and energy balance in experimental models.

Research Applications:
5-Amino-1MQ is being studied for its potential to:

• Support Weight Management Research by modulating metabolic rate and energy expenditure

• Investigate NNMT Inhibition in metabolic disease models

• Enhance Cellular Energy Metabolism via NAD⁺ pathway regulation

• Explore Age-Related Metabolic Decline and potential interventions

• Evaluate Lipid and Glucose Metabolism in preclinical studies

Storage and Handling:

• Store lyophilized powder at -20°C

• After reconstitution, store at 2–8°C and use promptly

• Avoid repeated freeze-thaw cycles

• Use aseptic techniques to maintain sterility

Product Specifications:

• Form: Lyophilized powder

• Concentration: 10 mg per vial

• Purity: ≥99% (HPLC Verified)

• Appearance: Orange powder

• Solubility: Soluble in bacteriostatic water, DMSO, or other suitable solvents for research use

Important Note:
For Research Use Only – Not for Human or Veterinary Use
This product is intended strictly for in vitro research and laboratory experimentation by qualified professionals. It is not a drug, food, cosmetic, or dietary supplement and has not been evaluated by the FDA. It is not intended to diagnose, treat, cure, or prevent any disease. The bodily introduction of this product into humans or animals is strictly prohibited by law. Any misuse, misbranding, or mislabeling of this product is a violation of federal regulations.

References:

• Kraus, D., et al. (2014). “Nicotinamide N-methyltransferase knockdown protects against diet-induced obesity.” Nature

• Hong, S., et al. (2018). “NNMT Inhibitors as a Therapeutic Option for Metabolic Disorders.” Journal of Medicinal Chemistry

• Policarpo, R., et al. (2020). “Development of Potent NNMT Inhibitors for Modulating Energy Metabolism.” ACS Medicinal Chemistry Letters