Tesofensine 500mcg Tablets (100ct)

Chemical Information:

• Molecular Formula: C₁₇H₂₃Cl₂NO
• Molecular Weight: 328.28 g/mol
• Chemical Name: (1R,2R,3S,5S)-3-(3,4-Dichlorophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylic acid methyl ester
• CAS Number: 402856-42-2
• Molecular Structure: Refer to Certificate of Analysis for detailed structural information.

Description:
Tesofensine is a synthetic small molecule extensively studied for its potential as a serotonin, norepinephrine, and dopamine reuptake inhibitor. Research indicates its role in regulating appetite, energy balance, and metabolic pathways, making it a valuable tool in experimental studies of obesity, metabolic syndrome, and neurological signaling. Provided in tablet or capsule preparations specifically for advanced laboratory research into metabolic processes, appetite modulation, and neurotransmitter regulation.

Research Applications:
Tesofensine is actively researched for potential roles in:

• Appetite Suppression Studies: Investigating mechanisms that regulate food intake, satiety, and body weight reduction.
• Metabolic Function: Examining effects on energy expenditure, thermogenesis, and fat metabolism in experimental models.
• Neurotransmitter Pathways: Exploring the impact on dopamine, serotonin, and norepinephrine signaling pathways and associated behaviors.
• Weight Management Research: Evaluating Tesofensine’s role in the modulation of metabolic parameters related to obesity.

Storage and Handling:

• Store tablets or capsules at controlled room temperature (15-25°C) in a dry, dark environment.
• Protect from moisture, heat, and direct sunlight exposure.
• Handle with care, observing standard laboratory practices to maintain product integrity.

Product Specifications:

• Purity: ≥98% (HPLC Verified)
• Appearance: White to off-white solid tablets or capsules
• Solubility: Soluble in DMSO and ethanol; limited aqueous solubility

Important Note:
This product is strictly FOR RESEARCH USE ONLY and is intended exclusively for in vitro research and laboratory experimentation by qualified professionals. It is not a drug, food, cosmetic, or dietary supplement, and has not been evaluated by the FDA. This compound is not intended to diagnose, treat, cure, or prevent any disease. The bodily introduction into humans or animals is strictly prohibited by law. Any misuse, misbranding, or mislabeling is a violation of federal regulations and may result in legal action under applicable federal, state, or local laws.

References:
Referenced scientific publications include:

• Astrup, A., et al. (2008). “The efficacy and safety of tesofensine for weight loss in obese individuals: A randomized controlled trial.” The Lancet.
• Hansen, H. H., et al. (2010). “Tesofensine, a novel triple monoamine reuptake inhibitor, induces appetite suppression by indirect activation of α₁-adrenoceptor and dopamine D₁ receptor pathways.” Neuropsychopharmacology.
• Sjödin, A., et al. (2010). “Effect of tesofensine on appetite sensations, energy expenditure and substrate oxidation in humans.” International Journal of Obesity.