Research compound reference
FOXO4-DRI
FOXO4-DRI is a synthetic retro-inverso peptide built from D-amino acids and achiral glycine. The material is a lyophilized powder of 99% or greater purity by HPLC, with a lot-specific Certificate of Analysis, for in vitro laboratory research. This page is a technical reference to the material's identity, chemistry, analytical testing and laboratory handling.
For research use only. Not for human or veterinary, diagnostic or therapeutic use.
Structure identifiers
The identifiers a laboratory uses to confirm it is working with FOXO4-DRI, as recorded in PubChem.1
Molecular formula
C228H388N86O64
Molecular weight
5358 g/mol
CAS number
2460055-10-9
InChIKey
WVZCDZFJLXBWHG-XXZPGMBKSA-N
Residue-level sequence is not shown here. The structure, including stereochemistry, is defined in the PubChem record.
What is FOXO4-DRI?
FOXO4-DRI is a synthetic retro-inverso peptide built from D-amino acids and achiral glycine. It is catalogued under CAS 2460055-10-9 and PubChem CID 167312269, with the molecular formula C228H388N86O64 and a molecular weight of 5358 g/mol.1
DRI stands for D-retro-inverso. In PubChem's systematic name every stereogenic alpha carbon is R-configured, which corresponds to D-amino acids.1 The material described on this page is a synthetic peptide intended as a laboratory reagent.
Handling
FOXO4-DRI is a dry solid as received in the laboratory. General handling guidance for lyophilized peptides applies.2
How each lot is tested
Each lot is tested by an independent third-party laboratory.3 The FOXO4-DRI certificate page names the testing laboratories and lists each lot's purity, net content and test date. Three measurements are reported.
Identity
Mass spectrometry
Checks that the measured molecular mass matches FOXO4-DRI. The calculated monoisotopic mass is 5354.98 Da.1
A matching mass is consistent with the expected composition. It does not confirm the order of residues.
Purity
High-performance liquid chromatography (HPLC)
Separates the material from synthesis-related impurities. Purity is reported as the main peak's share of the total detected signal.
Reported per lot. The Oasis Labs specification is 99% or greater.
Quantity
Net content
Measures the mass of material actually present in the sample tested.
Reported per lot on the Certificate of Analysis.
Technical notes
What does the Certificate of Analysis confirm?
Identity by mass spectrometry, purity by HPLC, and the net content of the sample. Mass spectrometry confirms molecular mass, not the order of residues.
Why do molecular weights for FOXO4-DRI differ slightly between sources?
The figure of 5358 g/mol is for the form described in the cited PubChem record. Salt forms carry extra counter-ion mass and are often registered separately.
Why is the material freeze-dried?
Peptides are most stable as dry solids. Moisture reduces long-term stability, so the material is lyophilized and kept sealed until use in the laboratory.
FOXO4-DRI lot certificates
Each listed FOXO4-DRI lot has its own certificate covering identity, purity and net content.
Catalogue entry: FOXO4-DRI
More from the research reference
References
- National Center for Biotechnology Information. PubChem Compound Summary for CID 167312269 (FOXO4-DRI). pubchem.ncbi.nlm.nih.gov/compound/167312269. Accessed 20 October 2026.
- MilliporeSigma (Merck KGaA). Handling and storage guidelines for peptides and proteins (technical article). merckmillipore.com. Accessed 14 October 2026.
- Oasis Labs. FOXO4-DRI Certificate of Analysis page, lot data and testing laboratories (certificate page), and testing methodology, myoasislabs.com/coa-process/.
References document the chemical identity, analytical characterisation and handling of this material.